What is a key factor in diagnosing disseminated intravascular coagulation?

A decreased platelet count is a key factor in diagnosing disseminated intravascular coagulation (DIC). In DIC, the coagulation cascade is activated inappropriately, leading to the formation of small blood clots throughout the blood vessels. This excessive clotting uses up platelets and clotting factors, resulting in a decreased platelet count.

As DIC progresses, the body may no longer be able to sustain adequate levels of platelets, thus contributing significantly to the diagnosis. Monitoring levels of platelets, along with other laboratory findings such as elevated levels of fibrin degradation products, helps in confirming the presence of DIC.

Other factors that are part of the diagnosis may include increased levels of fibrinogen degradation products and prolonged clotting times. However, the specific finding of a decreased platelet count is crucial in distinguishing DIC from other coagulation disorders.